What does it mean when a child's urine protein is three plus?

The urine protein test report may show three plus urine protein. This situation often indicates that there is a problem with the body. Many people understand this, but they don’t know what specific disease they have. Some parents asked: What’s going on with my child’s three plus urine protein? What should I do?

[1] Human urine contains a certain amount of protein, which is represented by (-) and (+) when the urine protein is greater than 150 mg. The more plus signs there are, the more protein leaked into the urine. The main reason for children's urine protein showing 3 plus signs is that the glomerular filtration membrane is damaged, resulting in increased filtration of protein by the filtration membrane. If not treated in time, the condition will further worsen. The phenotype of kidney intrinsic cells will transform, generating collagen fibrils that are not easily degraded, which will be deposited in the kidneys, gradually replacing healthy renal units and eventually developing into end-stage renal failure - uremia.

[2] The most common cause of a child's urine protein with 3+ plus signs is nephritis. The early symptoms of nephritis are not obvious, and only manifest as abnormalities in routine urine tests, such as urine protein or occult blood, accompanied by edema, hypertension, etc. Urinary protein appears in the inflammatory response stage of kidney disease. If it is not properly controlled at this stage, the disease will continue to progress and the final outcome will be kidney failure and uremia.

[3] If your child has 3 plus signs of protein in his urine, we recommend that you develop good living and eating habits in your daily life, and pay attention to preventing colds and excessive fatigue. The diet should be low in salt, fat, protein and high in vitamins. Avoid or eat less spicy and irritating foods. Prevent the recurrence of kidney disease caused by various adverse factors. Diet is only one aspect. If patients find 3 plus signs of urine protein, they need to receive standardized professional treatment in a timely manner.