What are the prevention and treatment methods for Helicobacter pylori in children?

There is a kind of bacteria growing in people's stomachs and intestines. Its main function is to protect people, but it can also cause Helicobacter pylori in children during adverse reactions, causing complications. It usually leads to chronic gastritis and chronic toxic diseases in patients. It is not difficult to completely eliminate Helicobacter pylori. As long as the patient can insist on taking medication and improve resistance during the treatment process, and defend against bacteria through his own resistance, the human body has strong resistance, which can ensure that the bacteria can be completely defeated, because the body with strong resistance can produce probiotics. The more probiotics reproduce, the more they can devour bacteria.

Helicobacter pylori

(Secretion of gastric acid and protease, protective effect of insoluble and soluble mucus layer, regular exercise, etc.) can resist the invasion of thousands of microorganisms entering through the mouth. Since the discovery of Helicobacter pylori on the surface of gastric mucosal epithelial cells, it has been recognized that Helicobacter pylori is almost the only culprit that can break through this natural barrier. Goodwin likened the destructive effect of Helicobacter pylori on the gastric mucosal barrier to the destruction of the "roof" causing disastrous consequences inside the house, so it is called the "leaky roof" theory.

Currently, most of the research on the infection routes of Helicobacter pylori can be classified into this theory. They mainly include: ① factors that enable Helicobacter pylori to penetrate the mucus layer and settle on the surface of gastric epithelial cells; ② toxin factors that destroy gastric epithelial cells; ③ various inflammatory cells and inflammatory mediators; ④ immune response substances, etc. [1]

These factors constitute the basic pathological changes in the Helicobacter pylori infection pathway, namely various types of acute and chronic gastritis. Among them, the most important attention in recent years is the role and molecular biology research of vacuolating toxin vaca, cytotoxin-associated protein caga, and urease.

Prevention and treatment methods

Medical scientists believe that it is not difficult to completely eliminate Helicobacter pylori. After 1 to 2 weeks of treatment, 90% of people infected with the bacteria can have Helicobacter pylori completely eliminated from their bodies. They suggested that a nationwide survey should be conducted, and at least people who have undergone gastric surgery, have had gastric disease, or have relatives with gastric cancer should be tested for Helicobacter pylori, and those infected should be given bactericidal treatment, which would hopefully control gastric cancer.

Fold to edit this section Detection method

Cardiac breath test

Since the successful isolation and culture of biopsy specimens taken through gastroscopy in 1983, many methods have been developed for the diagnosis of Hp infection, including bacteriology, pathology, serology, isotope tracing, molecular biology, etc. But in general, from the perspective of specimen collection, it can be divided into two categories: invasive and non-invasive.

Invasive methods

It mainly refers to the method of obtaining a biopsy specimen through gastroscopy, which is the current routine method in the field of gastroenterology. It includes bacterial isolation and culture, direct smear, rapid urease test, and drug sensitivity test.

Non-invasive methods

It mainly refers to the method of diagnosing Hp infection without taking biopsy specimens through gastroscopy. This type of method includes two major categories: serology and isotope tracing.