What is the cause of neonatal hemangioma?

Hemangioma is a common benign tumor of the skin blood vessels. It usually appears soon after a baby is born. There are many causes of its occurrence, and the main sites of occurrence are the facial skin, subcutaneous tissue, and oral mucosa, such as the tongue, lips, and floor of mouth. The causes are described below.

Hemangioma is a benign tumor that occurs in vascular tissue. It is mainly a vascular malformation caused by abnormal vascular development during embryonic development, abnormal vascular development or differentiation. It is a true tumor caused by abnormal proliferation of vascular endothelial cells. Although hemangiomas are generally congenital, the causes of their formation are different for each patient and can only be determined by a comprehensive examination at a regular hemangioma specialty hospital. There are many factors that lead to the occurrence of hemangiomas, and there is no generally accepted and affirmative statement so far.

It is generally believed that parents' genetics, endocrine disorders, hypertension and other diseases, environmental pollution or microbial infection during pregnancy can affect fetal vascular development. There are many studies on the correlation between the mother's hormone levels and the occurrence of infant hemangioma. It was found that the incidence of hemangioma in children of mothers who took contraceptives before pregnancy was significantly increased; the mother's estrogen level was positively correlated with the incidence of hemangioma in the child, that is, children whose mothers had high estrogen levels were more likely to develop hemangioma.

On this basis, many scholars have proposed that as the baby is born and breastfeeding is weaned, the hormone level from the mother in the baby's body gradually decreases, which leads to the natural regression of the baby's hemangioma. Some scholars also use hormones and estrogen receptor inhibitors to treat hemangiomas based on this theory.