What is the cause of juvenile granulosa cell tumor?

Once it is related to tumors, it is considered bad. In many cases, we must face this problem squarely, face our own health, and go to the hospital for regular check-ups. This is very good. Timely treatment and timely detection are very good and beneficial to our physical health. They are all very good. Face your own health squarely.

Incidence and age of onset Ovarian tumors are relatively rare in childhood and childhood. According to statistics, ovarian sex cord stromal tumors account for 5%-7% of all ovarian tumors and less than 10% of ovarian malignant tumors. In childhood and adolescence, granular cell tumors are the main types, accounting for about 5% of all granular cell tumors, but they show a different tumor biological characteristics, and about 90% of patients are prepubertal females at the time of diagnosis, which is called juvenile granular cell tumor. In a clinicopathological analysis of the first patients with juvenile granulosa cell tumor, 44% were less than 10 years old. Pathologically, the appearance and cross-section of juvenile ovarian granulosa cell tumor are basically the same as those of adult granulosa cell tumor. In a few cases, the cross-section of the tumor may appear pink and fish-like. The size is 3-32cm and has a capsule. The histological structure can be completely solid cells or completely follicular. In most cases, these two structures exist in a mixture in different proportions. The typical morphology has the following characteristics: the tumor cells grow in diffuse macrofollicular manner, with mucus-positive secretions in the follicles, a large number of luteinized cells and varying amounts of theca cell components, the tumor cells have no nuclear grooves, have certain atypia, and more mitotic figures. Staging and metastasis and spread of surgical disease The current staging of epithelial ovarian cancer, determined by surgery and histological examination, is 88% for stage IA, 2% for stage IB, 8% for stage IC, and 3% for stage II. Of note, extraovarian extension is uncommon during surgical exploration.

Juvenile granulosa cell tumor cannot be said to be cancer. It belongs to the category of ovarian sex cord stromal tumors. The WHO biological behavior code is 1. It is a borderline tumor with undetermined biological behavior. Only about 5% of them are invasive and most of them appear within 3 years (regular check-ups are very important). The prognosis is still relatively good, but the prognosis is relatively poor at clinical stage II and above.

I personally think chemotherapy is not necessarily necessary if the clinical stage is stage I. However, if metastasis has already occurred during surgery, then it is necessary to consider it separately.

: Patients with granulosa cell tumors have a 10 times higher chance of developing endometrial cancer than normal people. Granular cell tumors are also prone to be combined with uterine fibroids, which aggravates the symptoms of irregular vaginal bleeding. 6% of patients may have breast cancer, when the tumor occurs in postmenopausal women.

Suggestions: Postmenopausal bleeding is a typical clinical symptom, and other symptoms include breast swelling, breast enlargement, and rightward shift of the squamous epithelium maturation index in vaginal smears.

The above is the cause of juvenile granular cell tumor. It is very correct to discover and treat it in time. Only you know your own body, and only you can protect your own health. This will be beneficial to your health. You have to protect your own body. Protect your own health well, and you will work harder when doing anything.