Will Down syndrome affect the intelligence of babies?

The birth of a baby should be a happy and warm occasion, but as the baby grows older, every step of development becomes a concern for many parents. Only by ensuring the baby's healthy physical development can we avoid some problems. If a baby with Down syndrome is born accidentally due to genetic reasons, we can judge from the system that it will generally affect normal intelligence and walking, and in severe cases it will lead to drooling and dull eyes. These must be diagnosed in a timely manner.

symptom

Children with Down syndrome have many obvious symptoms in appearance and physique. Their intelligence is lower than that of normal children, usually with an IQ of only 40 to 60, but they have a gentle personality. Children with this disease have delayed development and low muscle tone, which makes them learn to sit, stand and walk later than normal children. They also have very distinctive facial features that make them easy to identify. Children with this disease usually have eyes that are far apart, slanted upwards, a flat nose bridge, and small mouths, teeth and ears. Most patients have ape-shaped palm lines (commonly known as broken palms), special hoof-shaped fingers, and the distance between the first and second toes is particularly wide.

In the past, the life expectancy of patients was very low, but now the average life expectancy of patients has increased to around 50 years, which is only slightly lower than that of normal people.

Down syndrome baby check

Down syndrome screening test is the abbreviation of prenatal screening test for Down syndrome. The purpose is to determine the risk of the fetus suffering from Down syndrome by testing the pregnant woman's blood. If the Down screening test results show that the fetus is at a higher risk of suffering from Down syndrome, further confirmatory tests should be carried out - amniocentesis or chorionic villus sampling.

Down syndrome screening can detect 60-70% of children with Down syndrome. It should be made clear that the Down syndrome screening test can only help determine the chance that the fetus has Down syndrome, but it cannot determine whether the fetus has Down syndrome. That is to say, when the blood test index is high, the chance of having a baby with Down syndrome is higher, but it does not mean that there must be something wrong with the fetus. Just as older pregnant women over 35 have a higher chance of having a baby with Down syndrome, it does not mean that their fetuses will definitely have problems. On the other hand, even if the test index is normal, it cannot guarantee that the fetus will not be sick.

Pregnant women whose Down syndrome screening index exceeds the normal level should undergo amniocentesis or chorionic villus sampling. Only if the results of amniocentesis or chorionic villus sampling are normal can the possibility of Down syndrome be 100% ruled out.

chromosome

Patients have a special chromosomal karyotype, that is, an extra chromosome 21[1]. The typical 21-trisomy, i.e. 47,XX(XY)+21 karyotype, is the majority, with a smaller number of translocations and the least mosaics.