Can neonatal sepsis be cured?

Neonatal sepsis is a particularly harmful disease. If it is not treated in time, it can easily cause damage to the child's internal organs, and can cause great harm to the child's intellectual development, hearing, etc. Under normal circumstances, simple sepsis will not cause sequelae as long as it is treated in time, and will not affect the child's health. The key lies in timely symptomatic treatment.

1. Etiology treatment:

Timely selection of appropriate antimicrobial drugs is the key to treatment. Antibiotics with bactericidal effects were selected based on bacterial culture and drug sensitivity tests. For example, penicillins are used for G+ bacteria, new penicillins or first-generation cephalosporins, lincomycin, etc. are used for enzyme-producing strains; ampicillin, ribosomycin or second- and third-generation cephalosporins are used for G- bacteria. When the pathogen is unclear, drugs with a broader antibacterial spectrum can be used. Severe infections can be treated with combination therapy, but attention should be paid to the resulting disturbance of the bacterial flora and superinfection. In order to achieve effective blood drug concentration as quickly as possible, the drug should be administered intravenously. The course of treatment varies depending on the blood culture results, efficacy, and the presence or absence of complications. It is generally 7-14 days. Those with complications should be treated for more than 3 weeks.

2. And lesion removal:

Local omphalitis, skin purulent foci, oral mucosal ulcers, etc. should be treated accordingly to cut off the source of infection.

3. Immunotherapy:

It can directly supplement various immune factors and antibodies in the blood of newborns, enhance immune function and promote disease recovery. Methods include multiple small-volume transfusions of fresh whole blood or plasma, exchange transfusion therapy, granulocyte transfusion, and immunoglobulin and immune RNA therapy.

4. Supportive therapy:

Rest in bed, strengthen nutrition, supplement appropriate amounts of vitamins, and ensure calorie supply. Maintain water, electrolyte and acid-base balance. Blood transfusion, plasma, albumin and immunoglobulin were given when necessary. Physical cooling can be given when the fever is high.

5. Symptomatic treatment:

Use physical methods to keep the child's body temperature normal. Oxygen can be administered when cyanosis occurs. People with circulatory disorders should replenish blood volume and use vasoactive drugs. Sedatives and anticonvulsants can be used to treat irritability and convulsions. Dehydrating agents should be used when there is cerebral edema.