What causes rheumatoid arthritis in children?

In today's life, no matter what disease it is, people of all ages are prone to get it. Rheumatoid arthritis is not only a disease for adults, but also for young children. What causes rheumatoid arthritis in children? Does this disease have a great relationship with the child's daily life? Let us take a closer look at the relevant content below.

The pathological changes of childhood rheumatoid arthritis are mainly joint lesions. It is a chronic non-suppurative synovitis. In the early stage, the synovial membrane of the joint is congested and edematous. Accompanied by infiltration of lymphocytes and plasma cells. The synovial effusion increases and the synovial membrane proliferates to form villous protrusions in the joint cavity. The synovitis continues to progress and enters the late stage. Synovial villous hyperplasia involves articular cartilage. And form pannus. Cartilage can be absorbed. Subchondral bone is eroded. Subsequently, the joint surfaces adhere to each other and the joint cavity is replaced by fibrous tissue. Cause joint stiffness, deformity or subluxation.

1. Systemic juvenile rheumatoid arthritis Systemic juvenile rheumatoid arthritis Approximately 20% of JRA patients show this type.

2. Rheumatoid factor-negative polyarticular JRA In 20% to 30% of patients with rheumatoid factor-negative polyarticular JRA, multiple joints are affected within a few months of onset without obvious systemic manifestations.

3. Rheumatoid factor-positive polyarthritis type JRA Rheumatoid factor-positive polyarthritis type JRA This type is characterized by polyarthritis (>4 joints) with positive rheumatoid factor (RF). They account for 5% to 10% of JRA, most of them are over 8 years old and most of them are women.

4. Oligoarticular JRA About 50% of patients with oligoarticular JRA are limited to one or a few (≤4) joints affected within the first 6 months of the disease or even throughout the entire course of the disease, and usually large joint lesions occur. Asymmetrical distribution.

The above content is an introduction to the causes of rheumatoid arthritis in children and the symptoms of childhood rheumatoid arthritis. Only through detailed understanding can the disease be better prevented and treated. Keeping children away from the pain of the disease is what parents should do most. Through the introduction of the causes, we learned about the situation of children suffering from this disease.