Treatment of neonatal ABO hemolytic disease

The treatment method of neonatal ABO hemolytic disease is something that many parents want to fully understand. Because their newborn children have this disease, many parents are particularly worried, so they want to fully understand the treatment methods. The following content gives a detailed introduction so that parents can fully understand it and take their children through treatment and recovery as soon as possible.

Clinical manifestations

Clinical manifestations are related to the degree of hemolysis:

1. Jaundice

The main clinical manifestation is early onset of neonatal jaundice. In most cases, the skin becomes obviously yellow within 24 to 48 hours after birth and the disease worsens rapidly.

2. Anemia

Anemia of varying degrees may occur when neonatal jaundice appears and after the jaundice subsides. It is mainly due to the destruction of a large number of red blood cells when hemolysis occurs. In the neonatal period, a hemoglobin level lower than 145 g/L is considered anemia.

treat

1. Light therapy

It is the simplest and most effective way to lower serum bilirubin. When serum bilirubin reaches the phototherapy standard, phototherapy should be performed in time. The phototherapy standards are formulated based on the presence or absence of complications at different gestational ages and at different days of age.

2. Medication

(1) Early application of intravenous immunoglobulin has better clinical effect.

(2) Albumin increases the binding of free bilirubin and reduces the occurrence of bilirubin encephalopathy.

3. Blood transfusion

When the serum bilirubin level reaches the transfusion standard according to different gestational ages and different days of age, transfusion therapy is required. Only severe cases of ABO hemolytic disease require exchange transfusion therapy.

4. Prevent hypoglycemia, hypocalcemia, hypothermia and electrolyte imbalance.

Treatment methods for neonatal ABO hemolytic disease. After fully understanding the treatment methods, parents should pay attention to the disease when their children get it, so as not to delay it for too long and cause serious physical harm to their children. It is best to have the children examined and treated in a large hospital so that they can recover as soon as possible.