How to treat Henoch-Schonlein purpura nephritis in children

How to treat Henoch-Schonlein purpura nephritis in children

Nowadays, more and more people suffer from kidney diseases. We all know that kidney is one of the most important organs in a person. It can help us filter out toxins in urine. Kidney is even more important for men. It is the key to men's reproduction of the next generation. Recently, there is a kidney disease called purpuric nephritis, which few people know about. Today I will introduce to you purpura nephritis.

Purpura nephritis, also known as Henoch-Schonlein purpura nephritis, is a systemic disease with allergic purpura and necrotizing vasculitis as the main pathological change, which can affect multiple organs in the body and manifest as kidney damage. In addition to skin purpura, joint swelling and pain, abdominal pain, and bloody stools, the main clinical manifestations are hematuria and proteinuria, which often occur within one month after skin purpura. Some patients may also have skin purpura and abdominal pain at the same time, while others may only have asymptomatic urine abnormalities.

The cause of the disease may be an allergic reaction caused by infections such as bacteria, viruses and parasites, or an allergy to certain drugs, foods, or plant pollen, insect bites, cold stimulation, etc. It is often related to the following factors:

1. Infection: One-third of cases have a history of upper respiratory tract infection 1 to 4 weeks before onset. Common pathogens include: viruses: Coxsackie, Epstein-Barr virus, adenovirus, varicella virus, rubella virus, hepatitis B virus, etc. Bacteria: Salmonella, Legionella, hemolytic Streptococcus, etc. Mycoplasma, amoeba, ascaris.

2. Drugs: antibiotics, sulfonamides, isoniazid, captopril, etc.

3. Food, fish, shrimp, crab, etc.

4. Cold stimulation, plant pollen, insect eggs, mosquitoes, vaccination, animal feathers, paint, etc.

Treatment principles

The treatment plan for purpuric nephritis should be selected according to the patient's age, clinical manifestations and degree of renal damage.

Actively control immune inflammatory responses, inhibit glomerular mesangial proliferative lesions, and prevent and delay the formation of chronic renal fibrosis.

General treatment

During the active period of the disease, you should pay attention to rest and maintain water and electrolyte balance. Patients with edema and heavy proteinuria should be given a low-salt diet, limit water intake, and avoid high-protein foods. To prevent recurrence of purpura and aggravate kidney damage, attention should be paid to preventing upper respiratory tract infections, clearing chronic infection lesions (such as chronic tonsillitis and pharyngitis), actively looking for possible allergens, and avoiding re-contact.

The above are some of the pathological characteristics and treatment methods of purpuric nephritis introduced by professionals. We must take kidney disease seriously. The kidneys are extremely important to a person, and we must protect our kidneys. For example, don't let your feet get cold and drink less alcohol. I hope the above content can help everyone.

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