Nowadays, there are many medicines for treating pediatric jaundice, but you must never use some medicines at home for treatment. Many medicines are very harmful to the baby's kidneys and will cause toxin accumulation. Therefore, before using the medicine, you must first obtain a doctor's examination and consent, and try to use medicines with fewer side effects. Do not use hormone drugs. The treatment of hemolytic jaundice is first of all to treat the hemolytic disease itself: eliminate the cause (such as red blood cell destruction caused by malaria requires radical cure of malaria to correct), remove the inducement (such as patients with G-6-PD deficiency should avoid eating broad beans and using drugs with oxidative properties), symptomatic treatment (such as using adrenocortical hormones and plasma exchange for autoimmune hemolytic anemia, splenectomy for patients with hereditary spherocytosis, certain types of thalassemia, and autoimmune hemolysis that is unresponsive to drug treatment, etc.); Secondly, symptomatic treatment for jaundice is used. Commonly used drugs in clinical practice include Yinzhihuang and Simitai, but it must be emphasized that if hemolysis is not resolved, it is difficult to reduce jaundice, and the effect is only temporary. (4) The normal methemoglobin reduction rate is >75%. This value is lower in patients with G-6PD (6-phosphate glucose dehydrogenase) deficiency, and further G-6PD activity measurement is required to confirm the diagnosis. (5) Blood, urine, cerebrospinal fluid culture, serum specific antibodies, C-reactive protein and erythrocyte sedimentation rate examination. If jaundice is suspected to be caused by infection, blood, urine, cerebrospinal fluid culture, serum specific antibodies, C-reactive protein and erythrocyte sedimentation rate examination should be performed. The white blood cell count in the blood routine test is increased or decreased, with toxic granules and nuclear left shift. (6) Liver function tests measure total bilirubin and conjugated bilirubin in the blood. Alanine aminotransferase is a more sensitive method to reflect liver cell damage. Alkaline phosphatase can be elevated in cases of intrahepatic bile duct obstruction or inflammation. (7) Abdominal ultrasound is a non-invasive diagnostic technique, especially suitable for newborns. Diseases of the biliary system, such as bile duct cysts, bile duct dilatation, gallstones, biliary atresia, and gallbladder absence, can all show the pathological conditions. (8) Electrophysiological examinations of auditory and visual functions, including brainstem auditory evoked potentials (BAEP), can be used to evaluate the functional status of auditory conduction nerve pathways, early predict brain damage caused by bilirubin toxicity, and help diagnose temporary or subclinical bilirubin neurotoxicity. |
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