Corpus callosum atrophy

The corpus callosum is very important to our human body. We should focus on protecting the corpus callosum to prevent some serious consequences, which may lead to some special diseases. There are some problems with the corpus callosum, such as corpus callosal atrophy. Some people may not understand the specific meaning of corpus callosal atrophy, which should be treated. So what does corpus callosal atrophy mean?

Cause: The corpus callosum is the most important large collection of myelinated fibers between the two cerebral hemispheres, connecting the two cerebral hemispheres and forming the roof of the lateral ventricle. It is one of the forebrain unions arising from the original homeoplate.

The earliest corpus callosum fibers can be seen in the embryo at embryonic day 74, and the corpus callosum is morphologically mature by embryonic day 115.

If the union block fails to induce axons from one hemisphere to cross the midline to the contralateral hemisphere, the corpus callosum cannot form. The corpus callosum is divided into four parts: the mouth, knee, body and pressure part. Its development order is from front to back, which is exactly the opposite of its maturation order. Intrauterine infection, ischemia and other reasons in the early embryonic period can cause abnormal development of the anterior brain and result in corpus callosum deficiency. Late lesions can cause dysplasia of the splenium of the corpus callosum. The body and knee are often affected first, and the knee and pressure part may be affected at the same time, but the knee is rarely affected alone, which is only seen in holoprosencephaly. However, Barkovich (1988) believed that corpus callosum hypoplasia is due to damage to the precursor stage of corpus callosum formation, rather than occurring during the corpus callosum formation period. Corpus callosum dysgenesis also has a genetic basis.