Causes of elevated lactate dehydrogenase in children

What is elevated lactate dehydrogenase in children? Generally speaking, mothers will be more nervous when it comes to their children's illnesses. Mothers should read the following article as soon as possible. What measures should mothers take to prevent it? Is it easy for children to have high lactate dehydrogenase levels? Is it a common disease in children? What kind of disease is high lactate dehydrogenase in children? Now, please come with me and look at the treatment method for high lactate dehydrogenase in children with your questions.

A concept

Lactate dehydrogenase is a glycolytic enzyme. Lactate dehydrogenase is present in the cytoplasm of all tissue cells in the body, with the highest content in the kidneys. Lactate dehydrogenase is an enzyme that catalyzes the conversion of pyruvate to lactate and is present in almost all tissues. There are six forms of isoenzymes, namely LDH-1 (H4), LDH-2 (H3M), LDH-3 (H2M2), LDH-4 (HM3), LDH-5 (M4) and LDH-C4, which can be separated by electrophoresis. The distribution of LDH isoenzymes has obvious tissue specificity, so it can be used to diagnose diseases based on its tissue specificity. In normal human serum, LDH2>LDH1. If myocardial enzymes are released into the blood, LDH1>LDH2. This indicator can be used to observe and diagnose myocardial diseases.

The reason for the increase

As for the reasons for high lactate dehydrogenase, there are the following aspects:

1. When the condition of a hepatitis B virus carrier worsens and becomes a hepatitis B patient, some liver cells are damaged and the levels of LDH4 and LDH5 in the serum will increase to varying degrees.

2. The treatment of hepatitis B, especially improper use of medication, and long-term use of the same medication can cause kidney toxicity. When nephrotoxicity occurs, the lactate dehydrogenase level in the serum will increase rapidly.

3. If hepatitis B is not treated appropriately and actively, it will develop to a certain extent and cause serious abnormalities in liver metabolism, leading to kidney failure, which will also cause an increase in lactate dehydrogenase levels.

4. Pulmonary infarction, pernicious anemia, shock and pleural effusion caused by tumor metastasis can cause elevated lactate dehydrogenase levels.

What to do

Elevated lactate dehydrogenase levels in serum are mainly caused by malignant tumors, hepatitis, cirrhosis and other diseases. Elevated lactate dehydrogenase levels are commonly seen in acute hepatitis, obstructive jaundice, myocarditis, malignant tumors, cirrhosis, liver cancer, muscular dystrophy, acute leukemia and pernicious anemia. Clinical medical practice shows that elevated serum lactate dehydrogenase in more than 80% of patients is caused by liver disease, especially acute hepatitis B, cirrhosis, liver cancer, etc. Therefore, if patients find that the lactate dehydrogenase level in their serum is no longer within the normal range, they should go to a liver disease hospital for testing in time and receive targeted treatment under the guidance of a doctor.

I believe that after reading the above content, everyone will have some understanding of the relevant content about high lactate dehydrogenase in children. Here is just a brief introduction. If a child unfortunately has high lactate dehydrogenase in children, we can give their parents some suggestions to help their children after reading this article. After all, every disease cannot be ignored, otherwise the disease will make our body collapse. Stay away from disease and embrace health. Prevent diseases at the very beginning and take good care of every baby.

A mother's responsibility is to protect every baby. Come on, moms.