When children are in the growth and development stage, parents usually pay great attention to their nutritional intake, so that their growth and development can become more complete. For example, they can take some drugs to nourish the brain nerves, which is especially good for children whose brain development is not so good. However, these drugs usually need to be taken under the doctor's advice. There are nine categories and more than 40 types of antipsychotic drugs in clinical use, among which the commonly used ones are phenothiazines, thioxanthenes, butyrophenones, benzamides and dibenzapines. Double-blind controlled studies have shown that as long as the dosage is appropriate and the treatment course is sufficient, the therapeutic effects of various antipsychotic drugs are roughly the same. The characteristics of drugs in the same category, such as phenothiazines, are basically similar in their effects and side effects. Clinicians should be proficient in the characteristics of 1 to 2 drugs in each category. For example, chlorpromazine of the phenothiazines has a strong sedative effect and moderate extrapyramidal side effects; trifluoperazine has a weaker sedative effect and a stronger effect on apathy and withdrawal, but is more prone to extrapyramidal side effects; telden of the thioxanthenes has a strong sedative effect and weaker extrapyramidal side effects; haloperidol of the butyrophenones has an extremely weak sedative effect, but is prone to extrapyramidal reactions and has a low therapeutic dose; clozapine of the diphenoxazepines and sulpiride of the benzamides both have few extrapyramidal side effects. The former has a strong sedative effect, while the latter has a weak one, and has become a commonly used drug second only to chlorpromazine. Some people divide antipsychotic drugs into two categories based on their commonly used therapeutic doses: drugs with therapeutic doses generally above 100 mg/d, such as chlorpromazine and telden, are classified as high-dose (low-potency) drugs; drugs with therapeutic doses generally within tens of milligrams, such as haloperidol and fluphenazine, are classified as low-dose (high-potency) drugs. The antipsychotic effect of fluphenazine is stronger than that of chlorpromazine, and its extrapyramidal side effects are also very significant, but its sedative effect is weaker. The antipsychotic effect of thioridazine is weaker than that of chlorpromazine, but it has fewer extrapyramidal reactions and stronger sedative effects. Pipothiazine is a powerful antipsychotic with a long-lasting effect, mainly used for chronic schizophrenia. Chlorprothixene has a strong sedative effect, but its other effects are relatively weak. It also has a weaker antidepressant effect and is suitable for schizophrenia accompanied by anxiety or anxious depression, menopausal depression, etc. Haloperidol has strong antipsychotic and extrapyramidal effects, strong antiemetic effect, and weak sedative and antihypertensive effects. It is often used for schizophrenia and vomiting. Penfluridol is a long-acting antipsychotic drug that is taken orally once a week. It is particularly suitable for maintaining and consolidating the therapeutic effect of chronic schizophrenia. Sulpiride is effective in treating acute and chronic schizophrenia and can also treat depression. It has almost no effect on the autonomic nervous system and mild extrapyramidal reactions. |
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