If children have repeated oral ulcers, parents must be alert to whether their children have Behcet's disease. Behcet's disease is a relatively common disease in children. Its obvious symptom is that it is easy to have repeated attacks, which is quite harmful to the health of children. It can easily cause children to cry, cause loss of appetite, etc. Certain medications must be used in time for treatment.
Beware of Behcet's disease if you have recurrent oral ulcers: Recurrent oral ulcers are mainly multiple and recurrent. If they recur, the chances of the ulcer surface healing will be very small, which means that before one ulcer is healed, another one will appear there. Therefore, the elasticity of our mucosa will drop sharply. After the elasticity of the mucosa drops, the protective film of our mucosa becomes particularly thin. If this happens repeatedly in the mouth, it will affect other parts of our body, such as the esophagus, digestive tract, and even our blood. This situation will also occur after the elasticity of our blood vessel walls drops. Therefore, if recurrent oral ulcers are not treated in time, they are likely to lead to Behcet's disease.
1. Viruses: In the early days, viruses were believed to be the cause of the disease, but this was not further confirmed by epidemiological, tissue culture, serological, animal inoculation, immunofluorescence, and electron microscopy tests. The infection report believes that the onset of the disease may be related to autoimmune abnormalities caused by lentivirus infection; some reports have found evidence of the relationship between HSV-1 and the disease, such as evidence of the relationship between anti-HSV-1 in the patient's blood and the disease, such as increased anti-HSV-1 antibody titers in the patient's blood, HSV-1 affects CD4 lymphocytes and causes immune abnormalities, and HSV-1 has DNA homologous to the peripheral blood lymphocytes of the disease. 2. Since some patients often suffer from diseases such as tonsillitis, pharyngitis and periodontitis, it is believed that the disease is related to the bacteria in these lesions. The study found that the anti-streptococcal antibody titer in the patient's serum was elevated; among the strains isolated from the patient's oral cavity, streptococcus was the most closely related, especially Streptococcus sanguinis, which gave positive results in intradermal tests and macrophage migration inhibition tests using its bacterial components; the 65-KDa heat shock protein test of streptococci can cause skin hypersensitivity reactions and systemic symptoms. These studies were mainly conducted by Japanese scholars. Although they believed that it played an important role in the onset of the disease, no consistent conclusion was reached.3. Mycobacterium tuberculosis Since 1964, there have been case reports in my country that believe the onset of the disease is related to tuberculosis infection, that is, the patient had tuberculosis before the initial onset of Behct disease, such as pulmonary tuberculosis, lymph node tuberculosis and other tuberculosis lesions. It can be an old lesion, but active lesions are the majority. Most OT tests are strongly positive; anti-tuberculosis drug treatment not only has a significant effect on the primary lesions, but also improves the related damage of Behcet's disease, and is therefore considered to be an allergic manifestation of tuberculosis bacteria. The 65-KDa heat shock protein of Mycobacterium tuberculosis is also related to the occurrence of this disease. |
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