What to do with psoriasis in children

Parapsoriasis is a very rare skin disease. People with this disease will have symptoms such as erythema, infiltration, scaly lesions, papules, etc. on their skin, which looks very scary. The most frightening thing about parapsoriasis is that people are not aware of it when it occurs, so many people take a long time to discover that they have parapsoriasis. So what should we do if children have psoriasis?

How to treat psoriasis

Parapsoriasis plaques

Although this type of skin lesions are not easy to disappear, the prognosis is good and there are no sequelae, so no treatment is necessary. Commonly used methods include external application of tar preparations or glucocorticoid preparations, simple ultraviolet irradiation or PUVA therapy. Other topical preparations that can also be tried include imiquimod, nitrogen mustard, carmustine, and tacrolimus.

Parapsoriasis plaques

Highly effective topical glucocorticoid preparations. Simple UVB irradiation or PUVA therapy should be performed once a day or every other day at the beginning, and the irradiation dose can be increased as appropriate until the skin lesions disappear. Then active maintenance treatment is required, such as once a week. The goal of treatment is to control the progression of the disease and may also help prevent malignant changes. Although external application of nitrogen mustard solution and irradiation with megavoltage electron beams are effective, they should not be used too early because of the significant adverse reactions. Vitamin D2 (250,000 U per day for 2 to 4 months), interferon-α and interleukin-12 can also be tried. Patients with this type should be closely observed for signs of malignant transformation, such as lymphadenopathy, hepatosplenomegaly, and induration of skin lesions. Suspicious skin lesions should be biopsied promptly.

According to specific treatment

Systemic treatment

Corticosteroids: can be tried for acute or progressive skin lesions to relieve the condition.

Psoralen: Combined with ultraviolet PUVA, UVB or corticosteroid therapy, it can inhibit the progression of the disease to mycosis fungoides.

Others: Vitamin D2, dapsone (DDS), chloroquine, tetracycline, etc. Patients with clinical and pathological findings consistent with early mycosis fungoides are often treated with UVB, PUVA, nitrogen mustard, or carmustine.

Topical treatments

Emollients, tar, corticosteroids or ultraviolet light therapy can be used according to different skin lesions. Infiltrative plaques can be treated with topical nitrogen mustard, and the therapeutic effect varies from person to person.