If you find that your baby's breasts are a little big, it may be a sign of precocious puberty. You can only know this after going to the hospital for a comprehensive examination, because the incidence of precocious puberty is becoming higher and higher. If you are not careful, your baby will have problems in this area. The treatment of this disease is not so effective now, and it can only be suppressed by drugs. (I) The purpose of treatment of central precocious puberty: 1. Inhibit or slow down the development of secondary sexual characteristics, especially prevent girls from menstruating. 2. Inhibit bone maturation caused by sex hormones and improve final height in adulthood. 3. Prevent psychosocial problems related to sexual development. (II) Etiological treatment Those caused by tumors should be surgically removed or undergo chemotherapy or radiotherapy; those with congenital adrenal hyperplasia should be treated with corticosteroids, and those with hypothyroidism should be treated with thyroxine. 3. Drug treatment 1. Gonadotropin-releasing hormone analogue (GnRHa): Its function is to competitively inhibit its own secretion of GnRH, reduce the secretion of pituitary gonadotropin, and restore estrogen to pre-pubertal levels. 2. Gonadal hormones: Using large doses of sex hormone feedback to inhibit the secretion of hypothalamic-pituitary gonadotropin, but it cannot improve the final height in adulthood. For example, danazol has anti-progestin and anti-estrogen effects, but its adverse reactions include hoarseness of voice, increased hair, and acne, so it is generally not used as the first choice drug. Medroxyprogesterone, also known as medroxyprogesterone, is no longer used to treat precocious puberty. Girls develop secondary sexual characteristics before the age of 8 in the following order: breast development → appearance of pubic hair → first menstruation. Boys develop secondary sexual characteristics before the age of 9: enlargement of the testicles and penis → appearance of pubic hair and beard → protrusion of Adam's apple and deepening of voice. Both men and women experience rapid increase in height and weight. Rapid bone growth can cause premature fusion of the epiphysis, affecting final height. It is of great significance in distinguishing true from false precocious puberty. The level is elevated in true cases, low in false cases, and significantly elevated in tumors. The secretion of FSH and LH also has age differences similar to those of sex hormones. In early adolescence, their secretion is characterized by sleep-induced pulsatile release. Therefore, a single blood sample often cannot reflect the actual secretion level. It is more meaningful to collect a 24-hour urine sample for measurement. |
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