What are the drugs for treating neonatal jaundice?

Neonatal jaundice is the most common phenomenon after a baby is born. Many parents are often very anxious when their baby shows jaundice, so they will blindly give the baby some medicine. In fact, there are many causes of neonatal jaundice, both physiological and pathological. Generally, physiological causes will disappear on their own without taking medicine, but pathological causes will easily affect the baby's physical health and even intellectual development if not treated in time. Let's take a look at the medicines for treating neonatal jaundice.

What are the drugs for treating neonatal jaundice?

【Western medicine】

1. Glucose and alkaline solutions Glucose can provide calories to children, nourish important organs such as the heart, liver, and brain, and reduce metabolic acidosis. In acidosis, the blood-brain barrier opens, which increases the amount of bilirubin entering the brain tissue. Alkaline solutions should be administered in time to correct acidosis and prevent bilirubin encephalopathy. Sodium bicarbonate dose (mEq) = base excess × body weight (kg) × 0.3.

2. Plasma or albumin supplies albumin linked to bilirubin, which can reduce free unconjugated bilirubin and prevent bilirubin encephalopathy. Plasma 25ml/time intravenous injection (100ml plasma contains 3g albumin, 1g albumin can bind to 8.5mg unconjugated bilirubin) or albumin 1g/kg plus 25% glucose 10-20ml intravenous drip, 1-2 times a day.

3. Enzyme inducers can induce the activity of glucuronyl transferase in the smooth endoplasmic reticulum of hepatocytes and reduce serum unconjugated bilirubin. Phenobarbital can also increase Y protein and promote the uptake of bilirubin by liver cells. Phenobarbital 5-8 mg/kg per day, nikethamide 100 mg/kg per day, both taken orally in 3 divided doses. Because it takes 2-3 days for the medication to show efficacy, it is important to start taking the medication as soon as possible. Using the two drugs together can improve the efficacy.

4. Adrenal cortical hormones can prevent the reaction between antigen and antibody, reduce hemolysis, and promote the binding ability of hepatocyte glucuronyl transferase to bilirubin. Take 1-2 mg/kg of prednisone orally three times a day, or 6-8 mg/kg of hydrocortisone per day or 1-2 mg of dexamethasone per day plus 10% glucose 100-150 ml intravenous drip. Patients suspected of infection should use it with caution under the control of effective anti-infective drugs.

【traditional Chinese medicine】

1. Xiaohuangli Granules: Artemisia capillaris 9g, Gardenia jasminoides 3g, Rhubarb 3g, Imperatae 10g, Centella asiatica 6g, Poria 6g.

2. Yinchenhao Decoction: Yinchen 1.5g, Gardenia 9g, processed rhubarb 3g, and liquorice 1.5g.

What are the treatments for neonatal jaundice?

3. Sanhuang Decoction: 4.5g Scutellaria baicalensis, 1.5g Coptis chinensis, and 3g processed rhubarb.

Tip: Although there are many types of medicines, you should choose according to actual needs. Western medicine takes effect quickly but has greater side effects, while Chinese medicine has fewer side effects but takes longer to take effect. Jaundice is mainly caused by the accumulation of bilirubin in the body. Excessive accumulation of bilirubin can cause serious symptoms. Therefore, if your child is found to have symptoms of jaundice, he or she should go to the hospital for examination in time.

The above is an introduction to the drugs for treating neonatal jaundice. After understanding, we know that there are many kinds of drugs for treating neonatal jaundice, but when taking the drugs, we must know whether the neonatal jaundice is physiological. In addition, during the treatment of jaundice, we must go to a regular hospital for examination and treatment. We cannot take drugs blindly. If the baby is breastfed, the mother must pay attention to eating light food.