How to treat nephrotic syndrome in children

Children with nephrotic syndrome have a relatively serious disease. For ordinary people, suffering from nephrotic syndrome means that they have lost their ability to work and have to live in this world like a waste. This is a huge burden for the family and a very painful thing for themselves. Children with nephrotic syndrome are especially affected. Let’s take a look at the introduction of how to treat children with nephrotic syndrome.

Western medicine is effective quickly in treating nephrotic syndrome in children, but the disease is prone to relapse; on the contrary, Chinese medicine is slow to take effect, but the effect is good and there is no relapse. Generally speaking, depending on the severity of nephrotic syndrome in children, Western medicine treatment of nephrotic syndrome in children generally adopts the following treatment steps.

The most commonly used ones are nitropropiodine, captopril and propranolol. The vasodilators dopamine or phentolamine given intravenously can provide a diuretic and lower blood pressure.

Hormone therapy

1. Short-term therapy: prednisone 2 mg/kg per day, total daily amount not exceeding 60 mg, taken orally in 3 divided doses, for 4 weeks. Then take it every other day for a total of 4 weeks. If urine protein turns negative 4 weeks after the start of treatment, take the medicine every other day for 4 weeks starting from the date of turning negative, and then gradually reduce the dosage. The total treatment course is 12 weeks. This method is rarely used in China.

2. Medium and long-term therapy: a commonly used method in pediatrics in China. Prednisone is taken orally at a dose of 2 mg/kg per day, divided into 3 doses. The treatment period can be extended by 2 weeks after urine protein turns negative, and the adequate treatment duration should not exceed 8 weeks. Later, change to 2 mg/kg every other morning for 4 weeks, and then reduce the dose once every 2 weeks, reducing 5 to 10 mg each time. The total course of treatment is 9 to 12 months.

From the above introduction, children with nephrotic syndrome are a very dangerous group. It is very scary for children to suffer from kidney disease because it is a huge pain for the family and a lifelong harm for the children. Therefore, when facing children with nephrotic syndrome, parents must take good care of them and treat them.