Clinical features of juvenile Parkinson's disease

What are the clinical features of juvenile Parkinson's disease? We all know that Parkinson's disease is an old age disease caused by lesions in the central nervous system. However, with the changes in the social environment, young people are burdened with pressure from study, work and life. If the pressure is not relieved for a long time, it can easily induce adolescent Parkinson's disease, which has caused great harm to many families. Because many people don't know much about juvenile Parkinson's disease, they don't pay much attention to it in normal times. Today we will talk about the clinical characteristics of adolescent Parkinson's disease to help everyone better understand this type of disease.

Adolescents with Parkinson's disease often have a family background of Parkinson's disease. The reason why they develop the disease early is because of gene mutation, not just a simple lack of dopamine that causes the brain tissue to be gradually destroyed. Its clinical characteristics are:

1. The age of onset is mostly between 10 and 25 years old, and there is often a familial tendency or obvious genetic history.

2. The disease course is short, progresses rapidly, and is easily accompanied by intellectual disability.

3. High muscle tone and slow movements are common, often accompanied by pyramidal tract signs and other system damage. Resting tremor is relatively rare.

4. Prone to oculomotor crisis (manifested by the eyeballs moving upwards involuntarily, which is the involuntary movement of the eye muscles).

5. Adolescent Parkinson's syndrome is often caused by viral encephalitis, brain trauma, carbon monoxide poisoning or drug use. Parkinson's syndrome often has positive findings on EEG, brain CT or MRI.

6. The effectiveness of compound levodopa in the treatment of primary Parkinson's disease is short-lived, and "long-term levodopa treatment syndrome" appears earlier.

Because of the extensive secondary lesions in Parkinson's syndrome, not only the substantia nigra is damaged, reducing the production of dopamine, but also the dopamine transport system and receptor system are damaged. Even after dopamine is supplemented, the effect is not good because the neural basis for its function has been lost.

The above are the clinical characteristics of adolescent Parkinson's disease. We hope that our introduction can help everyone better understand what Parkinson's disease is. We also hope that you will pay attention to your condition in your daily life, and go to the hospital for treatment in time when similar conditions occur. Finally, I wish all patients a speedy recovery.