How to treat Henoch-Schonlein purpura nephritis in children

It is not suitable for children's growth. If they suffer from Henoch-Schönlein purpura nephritis in children, it will cause great pain to the children. Henoch-Schönlein purpura nephritis in children will not only cause purpura symptoms on the child's skin, but in severe cases it may also cause swelling and pain in the joints and abdomen. Therefore, it is very important for every parent to know how to treat Henoch-Schonlein purpura nephritis in children.

According to different classification standards, there are three classification methods for childhood purpuric nephritis: ① Clinical classification of childhood purpuric nephritis, which is mainly based on the common clinical symptoms of children with purpuric nephritis; ② Pathological classification of childhood purpuric nephritis, which is mainly based on pathological changes after light microscopy of renal biopsy; ③ Immunopathological classification of childhood purpuric nephritis, which is mainly based on the deposition of immune complexes after fluorescent examination of renal biopsy, and is divided into IgA; IgA+IgG; IgA+IgM; IgA+IgG+IgM.

There is currently no specific treatment for pediatric purpuric nephritis. Symptomatic treatment is the main approach, with attention paid to protecting renal function.

1. Mild: No special treatment is required, symptomatic and supportive treatment is the main treatment, and contact with foods and drugs that cause allergies should be avoided. Sensitive antibiotics can be used when there is clear infection.

2. Acute nephritis syndrome type: mainly focus on lowering blood pressure, diuresis, controlling infection foci, and protecting renal function. Specific medication is the same as that for acute glomerulonephritis.

3. Nephrotic syndrome type: Adrenal cortical hormones can be used, usually prednisone.

4. Rapidly progressive nephritis and chronic nephritis types: Treatment is usually combined with hormones, cytotoxic drugs, anticoagulants and traditional Chinese medicine. Renal failure can be treated with dialysis. For rapidly progressive nephritis, methylprednisolone pulse therapy can be used early.

More than half of children with Henoch-Schonlein purpura can recover from kidney damage on their own, but a small number of children still have persistent hematuria, proteinuria and hypertension for a long time. About 2% of children develop end-stage nephritis, especially those with glomerulonephritis showing crescent formation in pathological examination. More than 80% of them develop end-stage nephritis within 1 year.

The above is an introduction to how to treat Henoch-Schonlein purpura nephritis in children. Because Henoch-Schonlein purpura nephritis in children does not have very obvious symptoms in the early stages, the child’s kidney damage is already quite serious when it is discovered. In order to detect the disease as early as possible, it is recommended that you give your child regular physical examinations.