Diabetes in children

Diabetes is mainly caused by different causes and some discovered mechanisms, so it is also a common disease in daily life. Diabetes can cause some insulin deficiency or functional disorders in the human body, leading to some protein or fat lesions, and some syndromes manifested by high blood sugar. Childhood diabetes mainly occurs in children under fifteen years old.

Children's diabetes is mainly caused by malnutrition and some non-insulin diabetes. In normal life, it is mainly the destruction of insulin cells caused by genetics and immune environment, which is also very critical. Children's diabetes is mainly manifested by nausea, vomiting, abdominal pain, joint pain, and deep and rapid breathing.

Prevention research on type 1 diabetes began in the 1970s. The method for measuring ICA was calibrated using JDF units in 1989. The Swedes reported that 405 newly diagnosed type 1 diabetes patients and 321 normal people matched with age and gender measured ICA in their blood. The positive rate of patients was 96% (389/405), and that of controls was 2.8% (9/321). During the 2-year follow-up, 2 of the 9 subjects in the control group developed diabetes, and the ICA of the remaining 7 subjects was <40 JDF units and later turned negative. Joslin-Sacramento began testing ICA and/or IAA in 8,000 first-degree relatives of type 1 diabetes patients in 1983. Among the relatives, 16/1,723 (0.9%) were positive, and two people developed diabetes during a two-year follow-up. Later, a standardized intravenous glucose tolerance test (IVGTT) was performed on people who were ICA and/or IAA positive, measuring insulin 1 minute and 3 minutes after glucose injection. If the insulin value was less than 5% of the normal value, it indicated that diabetes would occur within 3 years. In recent years, the measurement of GAD has become a predictive indicator.

For the high-risk population (first-degree relatives) discovered. Large-scale preventive treatment studies with nicotinamide or insulin have been initiated in Europe and the United States for people who are ICA and/or GAD positive.

An international trial, the DENIS programme, is underway in Germany to investigate the use of nicotinamide to prevent type 1 diabetes in children aged <12 years.

Animal experiments have found that insulin can delay the onset of diabetes. The United States conducted a trial study called DPI-I. After identifying high-risk people for type 1 diabetes, they are divided into two groups and given either oral or injected insulin for prevention. The results are still awaited.

In short, the prediction and prevention of type 1 diabetes has begun to be studied. Due to the progress in the study of the pathogenesis of type 1 diabetes, there may be greater progress in the methods of prediction and prevention of type 1 diabetes, and it is expected that good results can be achieved.

The above is an introduction to childhood diabetes, which is manifested by nausea, vomiting, abdominal pain, joint pain, and deep and rapid breathing. As well as some symptoms of mental depression and drowsiness, some preventive care for children is also very critical. Timely care can timely diagnose and treat all diabetic patients, so in the disease of diabetes, some common treatments must be carried out in time.