What should I do if my child takes antipyretics without a fever?

Under normal circumstances, you should choose standardized medication according to the physical condition. If you blindly use the medication when the physical symptoms do not match, it will not only lead to the failure of the medication, but may also cause side effects. For example, many children are naughty and eat antipyretics as candy when they do not have a fever. This will cause many adverse reactions and may even cause complications.

Adverse Reactions

1. Gastrointestinal reactions include nausea, vomiting, and upper abdominal discomfort. Large doses can induce and aggravate ulcers and painless bleeding. Therefore, it should not be used by patients with ulcers.

2. Coagulation disorders prolong bleeding time and may cause bleeding in patients with severe liver damage, low prothrombin, vitamin K deficiency and hemophilia. Patients should also stop using the drug one week before surgery to prevent bleeding. It should not be used during labor to avoid prolonging labor and increasing postpartum bleeding.

3. The most common allergic reactions are urticaria and asthma. The occurrence of asthma is related to the inhibition of PG synthesis. Epinephrine is ineffective for "aspirin asthma", which can be treated with corticosteroids. It is contraindicated in patients with asthma, nasal polyps and chronic urticaria.

4. Salicylic acid reaction: Taking large doses may cause dizziness, nausea, vomiting, tinnitus, hearing loss and other symptoms. Severe cases may lead to hyperventilation, acid-base imbalance, high fever, mental confusion and coma. Treatment: Stop medication immediately. Sodium bicarbonate was dripped intravenously to promote drug excretion.

5. Reye's syndrome. People with viral infections such as chickenpox or influenza should use aspirin with caution and can use paracetamol instead.

6. Kidney damage.

interaction

(1) When aspirin is used in combination with coumarin anticoagulants, sulfonylurea hypoglycemic drugs, phenobarbital, phenytoin sodium, and glucocorticoids, the effects of the above drugs may be increased due to the mutual replacement of plasma protein binding, such as prolonged bleeding time, hypoglycemia, and ulcer induction.

(2) Aspirin interferes with the secretion of methotrexate from the renal tubules and increases the latter's toxicity. When used in combination with furosemide, it competes with the renal tubular secretion system, thereby reducing the excretion of salicylic acid and leading to cumulative poisoning.

(3) Aminophylline or other alkaline drugs such as sodium bicarbonate can reduce the efficacy of aspirin, and acidic drugs can increase the blood concentration of salicylic acid.

(4) When aspirin is used in combination with non-steroidal anti-inflammatory drugs such as ibuprofen, the latter's blood levels can be significantly reduced and gastrointestinal adverse reactions can be increased.