Allergic purpura is a relatively common disease at present, which causes considerable harm to the patient's body. Allergic purpura mainly causes abnormal reactions in the microvessels, so some purple symptoms will appear on the body for a moment, and most of them are caused by food allergies, drug allergies, and insect bites. First find out the symptoms of the disease and then treat it. What causes Henoch-Schonlein purpura? Henoch-Schonlein purpura, also known as allergic purpura, is a relatively common microvascular allergic hemorrhagic disease. Causes include food allergies, drug allergies, pollen, infections caused by insect bites, allergies, but allergies are often difficult to determine the cause. It is more common in children and adolescents. There is often a history of upper respiratory tract infection within 1 to 3 weeks of onset. It manifests as skin petechiae that appear around the joints of the lower limbs and buttocks. Purpura is symmetrically distributed, crop-like, of varying sizes and depths of color, and can merge into flakes. It usually gradually subsides within a few days, but may recur. Patients may have gastrointestinal symptoms, such as paroxysmal abdominal cramps or persistent dull pain; joint pain; kidney symptoms, such as proteinuria and hematuria, mostly in children. Treatment includes identifying the cause of the allergy and avoiding it as much as possible; using antihistamines such as diphenhydramine, promethazine, chlorpheniramine, and corticosteroids. What are the characteristics of Henoch-Schonlein purpura? Most patients have symptoms and history of upper respiratory tract infection 1 to 2 weeks before the onset of the disease. Usually, the rash is brown-red maculopapules that protrude from the skin surface, do not fade when pressed, and appear alone or in combination, symmetrically distributed. It is more common on the extensor side of the limbs and buttocks, rarely invading the trunk, and is accompanied by itching or pain. Pigmentation may occur after the swelling subsides. In addition to purpura, urticaria may also occur. Angioneurotic edema, erythema multiforme, or ulcerous necrosis. Occasionally, purpura may occur on the oral mucosa and conjunctiva. Abdominal pain is common, angina, caused by blood entering the intestinal wall. There is obvious pain in the umbilical cord and right lower abdomen, which may also spread throughout the abdomen, but there is no general muscle tension and the tenderness is mild. It may be accompanied by nausea, vomiting, diarrhea and blood in the stool. Irregular bowel movements, intussusception, and palpable masses are common in children. Occasionally, intestinal perforation may occur. If it is not accompanied by skin purpura, it is often misdiagnosed as an acute abdomen. Nephritis is the most common complication of this disease, occurring in 12-65%. In general, purpura appears 1 to 8 weeks after onset and can be mild or severe, with some only causing short-term hematuria and others rapidly progressing to renal failure, but this is rare. |
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