What should we pay attention to when measuring C-protein in children with rheumatic fever?

Children's body resistance is relatively low so they are prone to rheumatic fever. Therefore, today I will explain to you about children's rheumatic fever and what parents should do when children have rheumatic fever. At the same time, let everyone know how to protect children when they have rheumatic fever? What kind of preparations should be made in daily life to prevent children from getting rheumatic fever?

Rheumatic fever is a systemic disease that is prone to recurrence. It is a non-suppurative inflammation that mainly affects the collagen fibers and matrix of connective tissue. It is characterized by rheumatic nodules (Aschoff nodules), which mainly invade the heart and joints, and can also affect the skin, brain tissue, blood vessels and serous membranes.

It is generally believed that this disease is the result of abnormal humoral and/or cellular immune response produced by the body after group A beta-hemolytic streptococcus (referred to as streptococcus) infects the pharynx. It is an autoimmune disease. Typical clinical manifestations include different combinations of migratory arthritis, carditis, marginal erythema (annular erythema), subcutaneous nodules, Sydenham chorea, fever, and toxemia. Repeated attacks can lead to permanent damage to the heart valves.

1. Rest The duration of bed rest depends on the degree of heart involvement and the state of cardiac function. Children without carditis in the acute phase should rest in bed for 2 weeks, then gradually resume activities and reach normal activity levels after 2 weeks. Children with carditis but no heart failure should rest in bed for 4 weeks, then gradually resume activities within 4 weeks. Children with carditis and congestive heart failure should rest in bed for at least 8 weeks, and gradually increase their activity over the next 2 to 3 months.

2. To control streptococcal infection, use large doses of penicillin intravenously for 2 to 4 weeks to completely eliminate the streptococcal infection. If you are allergic to penicillin, other effective antibiotics such as erythromycin can be used instead.

3. In the anti-rheumatic treatment of carditis, it is advisable to use adrenal cortical hormones early, prednisone 2mg/(kg·d), the maximum dose ≤60mg/d, taken orally in divided doses, and the dose should be reduced after 2 to 4 weeks, with a total course of 8 to 12 weeks; children without carditis can use aspirin, 100mg/(kg·d), the maximum dose ≤3g/d, taken in divided doses, and the dose should be gradually reduced after 2 weeks, with a course of 4 to 8 weeks.