Drug treatment for urinary tract infection in children

Children's urinary system is relatively fragile, so it is particularly easy to cause infection, and the infection is particularly serious. It is very painful for many children. Therefore, for many children, when a urinary tract infection occurs, they want to treat it with medication as soon as possible. So what are the methods of drug treatment for children's urinary tract infection? Let's take a look at the following introduction.

The following are drugs mainly used to treat urinary tract infections. Although they are available in major pharmacies, experts recommend that readers go to the hospital for formal examinations if they feel unwell and do not take medication without authorization to avoid serious consequences caused by inappropriate medication. 1 Amoxicillin: It is a broad-spectrum antibiotic that targets most positive bacteria and acts on skin and mucous membranes, soft tissues, and urinary system infections.

2Norfloxacin and levofloxacin: mainly used for middle respiratory tract and gastrointestinal infections, etc., and are more effective for urinary tract infections.

3. Ceftriaxone sodium: used for lower respiratory tract infections, skin, soft tissue and bone infections, urinary tract infections, hepatobiliary infections, intra-abdominal infections, gonorrhea, bacteremia, meningitis, etc. caused by sensitive bacteria such as Enterobacteriaceae. Intravenous injection.

4Cefuroxime: also known as Pioneer 6. Used for infections of the respiratory system, urinary system, skin and soft tissue, such as bronchitis, pneumonia, pyelonephritis, cystitis, ear, nose and throat infections, enteritis, dysentery, etc.

5. Ciprofloxacin: used for urethritis, cervicitis, etc. caused by chlamydia and mycoplasma.

Urinary tract infection

6-sulfonamide for urinary tract infection: Because it has a strong antibacterial effect on most Escherichia coli, has a high solubility in urine, is not easy to develop drug resistance, and is cheap, it is often the drug of choice for initial infection. The commonly used preparation is sulfamethoxazole (SME), which is often used in combination with the synergist trimethoprim (TMP) (i.e., co-trimoxazole SMZco). The dosage is 50 mg/(kg?d) taken in 2 divided doses. The general course of treatment is 1-2 weeks. To prevent crystals from forming in the urine, you should drink plenty of water. Use with caution in patients with renal insufficiency. 7. Pipemidic acid (PPA): It has a high urine excretion rate and is effective for treating urinary infections caused by Escherichia coli. Suitable for all types of urinary sensation. The dosage is 30-50 mg/(kg?d), taken orally in 3-4 times. There are few side effects, and only mild stomach discomfort may be tolerated. Use with caution in young children.

8 Furantanidine: It has a wide antibacterial range, is effective against Escherichia coli, and is not easy to develop drug resistance. The dosage is 8-10 mg/(kg?d), taken orally in 3 divided doses. It is easy to cause gastrointestinal reactions, so it is best to take it after meals. Can also be used in conjunction with TMP. For persistent infections that require 3-4 months of continuous treatment, furadine is a more appropriate choice.

9-Fluoropenic acid is a fully synthetic broad-spectrum antibacterial drug of the quinolone class, which has a strong antibacterial effect on Gram-negative and Gram-positive bacteria. The dosage is 5-10 mg/(kg?d), taken orally in 3-4 times. Because of its strong antibacterial effect, long-term use can lead to dysbacteriosis, so care should be taken when using it. Generally not used in young children.

10. Aminobencillin and bee pollen: Both are broad-spectrum antibiotics with good antibacterial effects and are often used to treat urinary infections. Although kanamycin and gentamicin have good antibacterial effects, they are highly nephrotoxic and have adverse effects on hearing, so they should be used with caution. Treatment course: In acute infection, if the selected antibiotics are sensitive to bacteria, a 10-day course of treatment can generally control the infection in most patients. If there is no fever, a 5-day course of treatment may be sufficient. After recovery, regular follow-up should be conducted for one year or longer. Because most relapses are due to reinfection, long-term therapy is not recommended for all patients.

Specific recommendations are as follows: ① For patients with infrequent relapses, treat the relapse as acute. ② For patients with repeated relapses, after the acute symptoms are controlled, a small dose (1/3-1/4 of the therapeutic dose) of SMZco, furantidine, pipemidic acid, or norfloxacin can be taken once a night before bedtime. The course of treatment can last for 3-6 months. For patients with repeated infections or with varying degrees of renal damage, the course of treatment can be extended to 1-2 years. To prevent the emergence of drug-resistant strains, combination therapy or rotation therapy can be adopted, that is, each drug is used for 2-3 weeks before being rotated to improve the efficacy.

The above content provides a detailed introduction to the drug treatment of urinary tract infection in children. Therefore, when a child has a urinary tract infection, do not wait, because waiting will cause serious damage to the urinary system. Therefore, after fully understanding the drug treatment, you should use drug treatment as soon as possible to allow the child's urinary tract infection to recover better as soon as possible.