What causes patent ductus arteriosus in premature infants?

Many premature babies will have patent ductus arteriosus. Many parents do not know the cause of this condition and are very worried about it. So what causes patent ductus arteriosus in premature infants? Only by understanding the causes can we do a good job of prevention and prevent the occurrence of diseases. Let us take a look at the following content. Find out what causes patent ductus arteriosus in premature infants.

There are many reasons for patent ductus arteriosus in premature infants, including gestational age, birth weight, maternal antenatal medication, premature infant-related diseases and postnatal interventions. Generally speaking, the younger the gestational age and the lower the birth weight, the higher the incidence of patent ductus arteriosus. The incidence of patent ductus arteriosus in patients with meconium-stained amniotic fluid, oligohydramnios, pregnancy infection and gestational diabetes is higher than that in other patients, and the incidence of patent ductus arteriosus in mothers who have not used hormones is higher than that in those who have used hormones. Among them, infection during pregnancy and temporary hypothyroidism are independent risk factors for PDA.

Experts remind that premature babies should pay attention to checking for patent ductus arteriosus and can undergo cardiac ultrasound examination. Newborns with small shunt flow and no obvious symptoms do not need surgery for the time being. They should continue to be observed and may recover on their own within 1 year old. If a child has shortness of breath, fatigue, difficulty breathing, or poor development, surgery can be performed before school age depending on the child's physical development and condition. Children with severe patent ductus arteriosus who present with cyanosis, rapid breathing, coarse breath sounds on auscultation of both lungs, and a grade 2 rough blowing murmur on auscultation of the heart should be scheduled for surgery immediately to avoid complications of pulmonary hypertension.

For premature infants with obvious symptoms of patent ductus arteriosus, the amount of fluid should be limited while ensuring that physiological needs are met during fluid rehydration, maintaining an appropriate high positive end-expiratory pressure and short inspiratory time, and attention should be paid to avoiding hypoxemia and acidosis. The best time for drug treatment is 4 to 7 days after birth, and indomethacin or ibufen can be used. If medical treatment is unsuccessful or a second course of treatment fails, surgical ligation may be used.

Regarding the question of what causes patent ductus arteriosus in premature infants, the above content I collected tells us the details. After reading the above content, do you understand the cause of patent ductus arteriosus in premature infants? If you still feel it is not clear enough, just come and ask our online experts.