Symptoms of high bile acid in newborns

Parents are often concerned about the health of their newborns, so they take them to the hospital regularly for check-ups to see if there are any abnormalities in their bodies. When testing liver function, most doctors will test the bile acid of newborns because bile acid can well reflect a person's liver function. Therefore, some newborns are tested to have high bile acid levels. So what are the symptoms if a newborn has high bile acid levels?

For normal people, the bile acids synthesized by the liver are mainly bile acid, chenodeoxycholic acid, and deoxycholic acid, lithocholic acid, ursodeoxycholic acid, etc. produced during metabolism, which can be collectively referred to as total bile acid. The index of total bile acid can well reflect the liver function of the human body. Once the index of total bile acid is abnormal, it should be taken seriously, otherwise it will cause great harm to human health.

There are many reasons that cause changes in the total bile acid value in the human body, but the main reason is that the liver has lesions, which leads to an increase in the bile acid content in the blood. Common liver diseases include acute hepatitis, chronic active hepatitis, cirrhosis, liver cancer and other diseases. When the human body suffers from these liver diseases, the total bile acid in the body will increase significantly.

In addition to liver disease, if the liver is substantially damaged, the liver cells' ability to synthesize bile acid will be reduced, resulting in an increase in the synthesis of chenodeoxycholic acid, which will ultimately lead to changes in the total bile acid value. In addition, if the human body suffers from chronic ethanol poisoning, primary liver cancer, bile duct obstruction, etc., it will also cause high levels of total bile acid.

The total bile acid reaction reflects the health of the human liver. If its index shows a high level, it indicates that the child's liver is diseased. The production and metabolism of bile acid are closely related to the human liver. Once its content increases significantly, it means that some changes have taken place in the liver cells of the human body. If the child does not receive treatment in time, it will not only affect the child's daily life, but may also threaten the child's life safety.

Diseases such as acute and chronic viral hepatitis, cholestasis, chronic ethanol poisoning, cirrhosis, liver cancer, etc. can all cause high levels of total bile acid. Moreover, these diseases will have a great impact on the child's body. Therefore, when the child's total bile acid level is high, the child should be taken to the hospital for treatment in time.