What diseases does the chickenpox vaccine prevent?

Vaccination against chickenpox in children is particularly helpful for children's health, so parents attach great importance to their children's vaccination to prevent diseases. The following content introduces in detail what diseases can be prevented by pediatric chickenpox vaccine? For many parents, they can have a comprehensive understanding of these aspects so that their children can be vaccinated with chickenpox vaccine in time to prevent diseases.

Varicella-zoster virus (VZV) belongs to the genus Herpesvirus, family Herpesviridae, and has 6 to 8 viral glycoproteins (G), which are associated with infection, production of neutralizing antibodies, viral replication, and virulence. VZV has only one serotype, and it is still unclear whether there is cross immunity with other herpes viruses. Humans are the only host of this virus.

VZV mainly enters the respiratory lymph nodes through droplets and replicates, producing the first viremia after 4 to 10 days. The virus then spreads through the lymph and blood and is phagocytosed by monocytes. After 4 to 6 days, the second viremia begins. The virus is released in large quantities into the blood, enters the epidermis through the capillaries, invades the skin and forms vesicles. Chickenpox occurs when the body lacks immunity after primary infection with VZV. And it has the ability to continue to penetrate into the human body. Herpes zoster is only seen in people who are infected with VZV and have had chickenpox. Although the pathogenesis is still unclear, it is believed that herpes zoster is the result of the virus lurking in the body after primary infection with VZV. When the body is in a certain pathological state and the defense function drops to a certain level, VZV revives and replicates in the nerve ganglion, and transmits retrogradely along the sensory nerves to the skin area innervated by the nerve endings and is released, producing a characteristic unilateral blister rash called herpes zoster.

Varicella is an infectious disease characterized by skin rash that occurs frequently in spring and autumn, with more than 90% of cases occurring among children. The main transmission routes are air droplets, direct contact and vertical transmission from mother to child. It can also be transmitted through contaminated utensils. It is easy to cause multiple outbreaks or outbreaks in childcare institutions.

Chickenpox has an acute onset but generally mild symptoms, such as low or moderate fever, headache, general discomfort, fatigue, loss of appetite, sore throat, cough, etc., which last for 1-2 days and then quickly enter the rash stage with dense, itchy blister rash.

If there are no complications, chickenpox will usually heal in about 1 to 2 weeks. Some children contaminate the wound when scratching the itchy rash, which causes subsequent bacterial infection such as pyoderma and cellulitis after the blisters rupture. In addition, there are some less common complications, including acute cerebellar movement disorders, encephalitis, pneumonia, bacterial infections of joints or bones, Reye's syndrome, etc.

The above introduces how children's chickenpox vaccine can prevent diseases. After a comprehensive understanding, parents must pay attention to it. Children must be vaccinated with the chickenpox vaccine as soon as possible. Only by vaccinating as soon as possible can your children get antibodies. When the body has antibodies, they can stay away from various diseases and avoid harm to their children.