Treatment of IGA nephropathy in children

Nowadays, the incidence of diseases among many children is getting higher and higher. Among them, IGA nephropathy in children has begun to wreak havoc recently. This disease causes great pain and torture to our children's bodies. For this reason, many parents are worried. They take their children to seek medical treatment everywhere, but their children's diseases rarely improve. Moreover, over time, this disease will also lead to other diseases. So, is there any good treatment for IGA nephropathy in children? Let us now learn about the best methods for treating IGA nephropathy in children.

method:

1. General treatment

(1) Drinking plenty of water may help push and flush small stones out with large amounts of urine. Increased urine output can also help control infection.

(2) Antispasmodic and analgesic M-type cholecystokinin receptor blockers can relax ureteral smooth muscles and relieve spasms. The usual dose is 20 mg. Intramuscular injection of progesterone can inhibit the contraction of smooth muscle and relieve spasm, and has a certain effect on pain relief and stone removal. The calcium channel blocker nifedipine has a certain effect on relieving renal colic. Alpha receptor blockers have a certain effect in relieving ureteral smooth muscle spasm and treating renal colic.

(3) Control infection. Urinary tract obstruction caused by stones is prone to infection, and magnesium ammonium phosphate stones often form in infected urine. This vicious cycle makes the condition worse. In addition to actively removing stones to relieve obstruction, antibiotics should be used to control or prevent urinary tract infections.

2. Treatment according to the cause of the different components

(1) Hypercalciuria ① Primary hypercalciuria can be treated with thiazides and potassium citrate. In addition to thiazides and potassium citrate, patients with absorptive hypercalciuria who cannot tolerate these drugs need to use sodium cellulose phosphate. Those with hypophosphatemia need to use orthophosphate instead. ② Actively treat associated diseases of hypercalcemia. When hypercalcemia crisis occurs, emergency treatment is required. First, use normal saline to expand the volume as quickly as possible, and use loop diuretics such as furosemide to increase urinary calcium excretion; bisphosphonates are mainly used to treat hypercalcemia, which can effectively inhibit osteoclast activity and reduce bone reabsorption. Surgical removal of the parathyroid glands is the treatment of choice for patients with primary hyperparathyroidism and symptomatic hypercalcemia or asymptomatic nephrolithiasis. When patients have symptomatic or obstructive renal stones in the absence of a hypercalcemic crisis, treat the stones first.

(2) Renal tubular acidosis is mainly treated with alkaline drugs to slow down stone growth and new stone formation and correct metabolic disorders.

(3) Hyperoxaluria Primary hyperoxaluria is difficult to treat. Vitamin B6 can be tried, starting with a small dose and increasing the dose as the effect decreases. At the same time, drink plenty of water and limit foods rich in oxalate, which can reduce the oxalate level in urine to normal.

The above content introduces us to the latest methods of treating IGA nephropathy in children. Through the above methods, we have a deeper understanding of IGA nephropathy in children. When our children have similar conditions, we can provide timely and effective treatment. At the same time, it can also save our parents from troubles and allow more people to live a healthier and happier life.