How to treat purpuric nephritis in children

Purpura nephritis in children is relatively common in clinical practice, and the treatment of allergic nephritis in children is also very important for people. Generally speaking, pediatric purpuric nephritis needs to be classified, and different types of treatments are also different. Of course, we also need to pay attention to the prognosis.

There is currently no specific treatment for purpuric nephritis in children. Symptomatic treatment is the main treatment, with attention paid to protecting renal function. After a child suffers from purpura, the treatment process will vary depending on the pathology. Therefore, special attention should be paid to protecting kidney function, because the recurrence of purpura can aggravate kidney damage.

1. Lightweight

No special treatment is required, and symptomatic and supportive treatment is the main approach, avoiding contact with allergy-causing foods and drugs. Sensitive antibiotics can be used when there is clear infection.

2. Acute nephritic syndrome

The main functions are to lower blood pressure, promote diuresis, control infection foci, and protect kidney function. Specific medication is the same as that for acute glomerulonephritis.

3. Nephrotic syndrome

Adrenal cortical hormones can be used, usually prednisone.

4. Rapidly progressive nephritis and chronic nephritis

The treatment is usually combined with hormones, cytotoxic drugs, anticoagulants and traditional Chinese medicine. Renal failure can be treated with dialysis. For rapidly progressive nephritis, methylprednisolone pulse therapy can be used early.

5. Prognosis

More than half of children with Henoch-Schonlein purpura can recover from kidney damage on their own, but a small number of children still have persistent hematuria, proteinuria and hypertension for a long time. About 2% of children develop end-stage nephritis, especially those with glomerulonephritis showing crescent formation in pathological examination. More than 80% of them develop end-stage nephritis within 1 year.