What to do if pituitary dysplasia

What to do if pituitary dysplasia

Many children will have pituitary dysplasia at birth. Do you know what pituitary dysplasia is? Pituitary dysplasia is very harmful to children, and it will cause greater harm to children in the future. In view of this phenomenon of pituitary dysplasia, children should be treated symptomatically to control and improve their diseases as best as possible. Children with pituitary dysplasia will have great deformities, be too short, and cause cardiovascular diseases. So what should children with pituitary dysplasia do?

Secondary pituitary dysplasia requires etiological treatment, such as craniopharyngioma should be operated on as soon as possible. When patients with idiopathic pituitary dysplasia have pituitary growth hormone deficiency, it is best to use growth hormone replacement therapy. These patients can grow taller after treatment with growth hormone. Several drug treatments are described below. They can be used alone or in combination. The key is to use them according to the patient's specific situation.

Growth hormone

It has been clinically proven to be effective since it was first used in 1958, but its source is limited, its price is high, and it has not yet been widely used. Usage: The general dosage is 1-2 mg each time, intramuscular injection, 3 times a week. 20-45 mg per month. Since human growth hormone is mostly secreted at night, it is best to inject the drug 1 hour before going to bed. The most significant effect is achieved 6 to 12 weeks after the start of treatment, and the height can increase by 5 to 10 cm in the first year. After long-term application, the growth rate slows down, increasing by 3 to 5 cm each year. The earlier you start this treatment, the better the results. If conditions permit, long-term treatment should be given until growth is basically stopped. If androgen drugs that promote protein synthesis are added, the therapeutic effect may be increased. Growth hormone and androgens have a synergistic effect on growth.

) Androgen

The synthetic anabolic steroid nandrolone phenylpropionate, also known as 19-demethyl-testosterone propionate, has a total monthly dose of 1 to 1.5 mg per kilogram of body weight, administered by intramuscular injection in divided doses, generally once a week. The appropriate age to start treatment is generally considered to be between 10 and 14 years old. Because nandrolone phenylpropionate promotes bone growth while promoting growth and development, the effect is often more significant at the beginning of medication, but the effect will be worse later. During treatment, excessive dosage should be avoided to avoid premature epiphyseal fusion. It is best to observe the bone age when using the product. If the bone age is less than 3 years old, it should not be used to avoid affecting the final height. A course of treatment with this medicine is 3 to 6 months, and the treatment can be repeated after 3 to 6 months of discontinuation.

⑶ Human chorionic gonadotropin; generally women can take it after the age of 16, and men can take it after the age of 19. The age of taking the medicine should not be too early, because it can promote epiphyseal fusion and ultimately hinder bone growth. Usage: intramuscular injection, 2 to 3 times a week, 3 to 6 months as a course of treatment.

If you are facing the phenomenon of pituitary hypoplasia, you must quickly choose these methods to treat yourself. When treating pituitary hypoplasia, you must remember to match the drugs reasonably and choose the most suitable drugs for treatment. If the pituitary gland is hypoplastic, it is very easy to develop pituitary dwarfism. Therefore, you must regularly check and treat the disease symptomatically during the treatment process.

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