Is diarrhea hereditary?

Stomach discomfort is a common problem in life. It can bring pain to people's bodies and have a great adverse effect on the rhythm of life. Stomach discomfort is mainly manifested in diarrhea and abdominal pain. Among them, diarrhea is a disease that has the greatest impact on the rhythm of life. It can cause dehydration in patients, etc. Is diarrhea hereditary? Let's take a look at the explanation below. I hope everyone can understand it.

Causes of diarrhea in children:

Type 1: Children with lactose intolerance

Whether it is human milk or cow's milk, the carbohydrates contained are lactose, which is only about one-sixth of the sweetness of sucrose. Some children have congenital metabolic defects and insufficient lactase activity in their intestines. After drinking dairy products, they are unable to break down lactose into glucose and galactose, so a large amount of lactose enters the large intestine. The bacteria in the large intestine break down the lactose into carbon dioxide and hydrogen, resulting in symptoms such as abdominal bloating, flatulence, abdominal cramps and even diarrhea.

These infants and young children are allergic to the protein in milk. Since the protein content in milk is as high as 3.5% (human milk is only 1.1%), and these infants and young children are allergic to foreign proteins, they are prone to allergic reactions such as diarrhea, indigestion and even urticaria (commonly known as "urticaria") after drinking milk. This type of infant is rare, with an incidence rate of only about 0.1%.

This is a recessive hereditary disease caused by a mutation in the twelfth pair of autosomal genes. Due to the lack of phenylalanine hydroxylase in the liver of the child, phenylalanine cannot be metabolized normally to produce tyrosine and accumulates in the blood in large quantities. At the same time, other harmful abnormal products (such as phenylacetic acid, phenyllactic acid, and phenylpyruvic acid) are produced, thus affecting the child's normal brain development (before the age of 6), causing damage to the nervous system, and causing dementia in the child. Every 100 ml of milk contains 150 mg of phenylalanine (every 100 ml of breast milk contains only 50 mg), so this type of children is not suitable for drinking milk or ordinary milk powder. Among the above three categories of infants and young children, this type of situation is the most special, but the relative incidence rate is also low, about 1/16500 in my country.